Imports System
Imports System.Reflection

Class C
  Public Sub M()
    Throw New NotImplementedException()
  End Sub
End Class

Class Sample
  Shared Sub Main()
    Dim t As Type = GetType(C)
    Dim inst As Object = Activator.CreateInstance(t)

    Try
      ' Type.InvokeMemberを使ってメソッドを呼び出す (呼び出し先で例外が発生する)
      t.InvokeMember("M", BindingFlags.InvokeMethod, Nothing, inst, Nothing)

    ' 呼び出したメソッドで例外が発生した場合、TargetInvocationExceptionがスローされる
    Catch ex As TargetInvocationException
      Console.WriteLine(ex)
      Console.WriteLine()

      ' InnerExceptionプロパティを参照してメソッドが実際にスローした例外を取得する
      Console.WriteLine("actual exception type: {0}", ex.InnerException.GetType())
    End Try
  End Sub
End Class

System.Reflection.TargetInvocationException: Exception has been thrown by the target of an invocation.
 ---> System.NotImplementedException: The method or operation is not implemented.
   at C.M()
   --- End of inner exception stack trace ---
   at System.RuntimeMethodHandle.InvokeMethod(Object target, Object[] arguments, Signature sig, Boolean constructor, Boolean wrapExceptions)
   at System.Reflection.RuntimeMethodInfo.Invoke(Object obj, BindingFlags invokeAttr, Binder binder, Object[] parameters, CultureInfo culture)
   at System.RuntimeType.InvokeMember(String name, BindingFlags bindingFlags, Binder binder, Object target, Object[] providedArgs, ParameterModifier[] modifiers, CultureInfo culture, String[] namedParams)
   at System.Type.InvokeMember(String name, BindingFlags invokeAttr, Binder binder, Object target, Object[] args)
   at Sample.Main()

actual exception type: System.NotImplementedException